On January 10, 2025, Columbia University unveiled an AI model trained on 1.3 million human cells, accurately predicting gene activity across any cell type. This breakthrough not only uncovered mechanisms behind pediatric leukemia but also delves into the genome's elusive 'dark matter.' By shifting biology from descriptive to predictive, this innovative approach promises to transform disease research and treatment strategies, blending cutting-edge tech with compassionate science for a healthier future.